Chapters 00:00 - Intro 0:43 - What are They? 1:37 - How it Helps Cartilage 2:34 - The GAIT Study 3:15 - The MOVES Study 4:21 - Which Supplement? 4:50 - How Much to Take? 5:17 - Cautions Glucosamine and chondroitin supplements have gained popularity for joint health, particularly in osteoarthritis. These supplements are widely used to improve joint function. What is Glucosamine? Glucosamine is a natural compound found in cartilage and is believed to play a crucial role in maintaining joint health. What is Chondroitin? Chondroitin, on the other hand, is a major component of cartilage and is thought to help maintain its elasticity and fluidity. As individuals age or experience conditions like osteoarthritis, the natural production of these substances may decrease, leading to joint discomfort and stiffness. Clinical studies on the efficacy of glucosamine and chondroitin supplements have yielded mixed results, with some suggesting potential benefits while others show limited impact. However, many individuals report experiencing relief from joint pain and improved mobility after consistent use of these supplements. It's important to note that the effectiveness of these supplements can vary from person to person, and individual responses may be influenced by factors such as the severity of joint issues, overall health, and lifestyle. GAIT STUDY: https://www.nejm.org/doi/full/10.1056... MOVES STUDY: https://www.nature.com/articles/nrrhe... Are Glucosamine and Chondroitin Effective? Cartilage is a main type of connective tissue in your body. Its biggest role is to protect and cushion the ends of your bones, which is why it’s found within your joints. But In people with osteoarthritis, this cartilage is wearing down, your bones are starting to rub against each other, and there is no cushion between them. Over time this can lead to pain and affect your joint mobility, which we often see in the knees, hips, hands, and spine and can be very uncomfortable. Glucosamine and Chondroitin Does it Work Also, be patient when you take this supplement. “It can take weeks for the effects to fully be brought on. This depends person to person of course and the severity of the osteoarthrisits. And in terms of safety, they are safe for most people as long as they are used according to the directions on the supplement label. Also you do want to check with your care team if you are taking warfarin as it can interact with it, if you have shellfish allergy, and same if you are a diabetic, check with them first because this supplement may affect blood sugar levels too.